MyBioSource.com's Rabbit Anti-PTPRE / PTP Epsilon Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, and Immunohistochemistry - fixed. The Rabbit Anti-PTPRE / PTP Epsilon Antibody was generated using PTPRE as the antigen and it reacts with Human, Canine, and Non-Human Primate.
Description
PTP epsilon, an R4 receptor protein tyrosine phosphatase, is composed of a short extracellular and two cytoplasmic protein phosphatase domains and has been shown to affect neuronal differentiation, endothelial cell growth, vascular development, and possibly mammary tumor development. It has been shown that the cytosolic form of PTP epsilon can be induced by IL-1 and TNF alpha in humans and is a negative regulator of IL-6- and LIF-induced Jak-STAT kinase signaling in rats